Paradigm Biocapital Advisors LP Quant / Systematic

CIK: 0001855655 · Show all filings

Period: Q4 2021 (Next →)

Filing Date: Feb 14, 2022

Total Value ($000): $350,154 (100.0% shares, 0.0% debt)

Holdings (24)

— MIRATI THERAPEUTICS INC 10.9%

Value ($000) $38,156 Shares 260,115 Est. Cost $146.69 Unrealized —

ASND ASCENDIS PHARMA A/S 8.4%

Value ($000) $29,349 Shares 218,158 Est. Cost $134.53 Unrealized —

ZNTL ZENTALIS PHARMACEUTICALS INC 7.2%

Value ($000) $25,254 Shares 300,434 Est. Cost $77.38 Unrealized 0.0%

VRDN VIRIDIAN THERAPEUTICS INC 6.8%

Value ($000) $23,903 Shares 1,209,051 Est. Cost $18.63 Unrealized 0.0%

— ARENA PHARMACEUTICALS INC 6.7%

Value ($000) $23,400 Shares 251,777 Est. Cost $92.94 Unrealized —

— GLOBAL BLOOD THERAPEUTICS IN 6.5%

Value ($000) $22,845 Shares 780,480 Est. Cost $29.27 Unrealized —

ARVN ARVINAS INC 6.3%

Value ($000) $22,056 Shares 268,519 Est. Cost $81.37 Unrealized 0.0%

LEGN LEGEND BIOTECH CORP 5.1%

Value ($000) $17,990 Shares 385,967 Est. Cost $46.61 Unrealized —

IOVA IOVANCE BIOTHERAPEUTICS INC 4.6%

Value ($000) $16,112 Shares 844,005 Est. Cost $22.02 Unrealized 0.0%

— SEAGEN INC 4.4%

Value ($000) $15,566 Shares 100,687 Est. Cost $154.60 Unrealized —

ARGX ARGENX SE 4.2%

Value ($000) $14,725 Shares 42,050 Est. Cost $350.18 Unrealized —

— IVERIC BIO INC 3.9%

Value ($000) $13,637 Shares 815,581 Est. Cost $16.72 Unrealized —

INSM INSMED INC 3.1%

Value ($000) $10,742 Shares 394,358 Est. Cost $28.59 Unrealized 0.0%

— SIERRA ONCOLOGY INC 2.9%

Value ($000) $10,325 Shares 474,945 Est. Cost $21.74 Unrealized —

SNDX SYNDAX PHARMACEUTICALS INC 2.8%

Value ($000) $9,918 Shares 453,091 Est. Cost $18.48 Unrealized 0.0%

GLPG GALAPAGOS NV 2.6%

Value ($000) $9,252 Shares 167,824 Est. Cost $55.13 Unrealized —

CCCC C4 THERAPEUTICS INC 2.4%

Value ($000) $8,332 Shares 258,746 Est. Cost $39.55 Unrealized 0.0%

KYMR KYMERA THERAPEUTICS INC 2.3%

Value ($000) $7,991 Shares 125,858 Est. Cost $58.25 Unrealized 0.0%

— VOR BIOPHARMA INC 2.1%

Value ($000) $7,313 Shares 629,342 Est. Cost $11.62 Unrealized —

ENTA ENANTA PHARMACEUTICALS INC 1.6%

Value ($000) $5,646 Shares 75,507 Est. Cost $78.47 Unrealized 0.0%

— OYSTER PT PHARMA INC 1.6%

Value ($000) $5,555 Shares 304,238 Est. Cost $18.26 Unrealized —

IMCR IMMUNOCORE HLDGS PLC 1.3%

Value ($000) $4,597 Shares 134,249 Est. Cost $34.24 Unrealized —

ESPR ESPERION THERAPEUTICS INC NE 1.2%

Value ($000) $4,196 Shares 839,257 Est. Cost $8.01 Unrealized 0.0%

— GRACELL BIOTECHNOLOGIES INC 0.9%

Value ($000) $3,294 Shares 545,388 Est. Cost $6.04 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	MIRATI THERAPEUTICS INC	260,115	$38,156	10.9%	$146.69	—	COM	60468T105
ASND	ASCENDIS PHARMA A/S	218,158	$29,349	8.4%	$134.53	—	SPONSORED ADR	04351P101
ZNTL	ZENTALIS PHARMACEUTICALS INC	300,434	$25,254	7.2%	$77.38	0.0%	COM	98943L107
VRDN	VIRIDIAN THERAPEUTICS INC	1,209,051	$23,903	6.8%	$18.63	0.0%	COM	92790C104
—	ARENA PHARMACEUTICALS INC	251,777	$23,400	6.7%	$92.94	—	COM NEW	040047607
—	GLOBAL BLOOD THERAPEUTICS IN	780,480	$22,845	6.5%	$29.27	—	COM	37890U108
ARVN	ARVINAS INC	268,519	$22,056	6.3%	$81.37	0.0%	COM	04335A105
LEGN	LEGEND BIOTECH CORP	385,967	$17,990	5.1%	$46.61	—	SPONSORED ADS	52490G102
IOVA	IOVANCE BIOTHERAPEUTICS INC	844,005	$16,112	4.6%	$22.02	0.0%	COM	462260100
—	SEAGEN INC	100,687	$15,566	4.4%	$154.60	—	COM	81181C104
ARGX	ARGENX SE	42,050	$14,725	4.2%	$350.18	—	SPONSORED ADR	04016X101
—	IVERIC BIO INC	815,581	$13,637	3.9%	$16.72	—	COM	46583P102
INSM	INSMED INC	394,358	$10,742	3.1%	$28.59	0.0%	COM PAR $01	457669307
—	SIERRA ONCOLOGY INC	474,945	$10,325	2.9%	$21.74	—	COM NEW	82640U404
SNDX	SYNDAX PHARMACEUTICALS INC	453,091	$9,918	2.8%	$18.48	0.0%	COM	87164F105
GLPG	GALAPAGOS NV	167,824	$9,252	2.6%	$55.13	—	SPON ADR	36315X101
CCCC	C4 THERAPEUTICS INC	258,746	$8,332	2.4%	$39.55	0.0%	COM STK	12529R107
KYMR	KYMERA THERAPEUTICS INC	125,858	$7,991	2.3%	$58.25	0.0%	COM	501575104
—	VOR BIOPHARMA INC	629,342	$7,313	2.1%	$11.62	—	COM	929033108
ENTA	ENANTA PHARMACEUTICALS INC	75,507	$5,646	1.6%	$78.47	0.0%	COM	29251M106
—	OYSTER PT PHARMA INC	304,238	$5,555	1.6%	$18.26	—	COM	69242L106
IMCR	IMMUNOCORE HLDGS PLC	134,249	$4,597	1.3%	$34.24	—	ADS	45258D105
ESPR	ESPERION THERAPEUTICS INC NE	839,257	$4,196	1.2%	$8.01	0.0%	COM	29664W105
—	GRACELL BIOTECHNOLOGIES INC	545,388	$3,294	0.9%	$6.04	—	SPONSORED ADS	38406L103