Location: Greenwich, CT
CIK: 0001856083 · Show all filings
Period: Q4 2021 (Next →)
Filing Date: Feb 14, 2022
Total Value: $1.417B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| KROS | KEROS THERAPEUTICS INC | 1,300,000 | $76.06M | 5.4% | $49.87 | 0.0% | COM | 492327101 |
| TVTX | TRAVERE THERAPEUTICS INC | 2,450,000 | $76.05M | 5.4% | $28.16 | 0.0% | COM | 89422G107 |
| BCYC | BICYCLE THERAPEUTICS PLC | 1,100,000 | $66.96M | 4.7% | $60.87 | — | SPONSORED ADS | 088786108 |
| — | IVERIC BIO INC | 4,000,000 | $66.88M | 4.7% | $16.72 | — | COM | 46583P102 |
| JAZZ | JAZZ PHARMACEUTICALS PLC | 500,000 | $63.7M | 4.5% | $131.42 | 0.0% | SHS USD | G50871105 |
| — | GLOBAL BLOOD THERAPEUTICS IN | 2,000,000 | $58.54M | 4.1% | $29.27 | — | COM | 37890U108 |
| BEAM | BEAM THERAPEUTICS INC | 700,000 | $55.78M | 3.9% | $85.62 | 0.0% | COM | 07373V105 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 1,900,000 | $53.98M | 3.8% | $24.65 | 0.0% | COM | 22663K107 |
| — | REPARE THERAPEUTICS INC | 2,100,000 | $44.29M | 3.1% | $21.09 | — | COM | 760273102 |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 500,000 | $42.37M | 3.0% | $82.16 | 0.0% | COM | 558868105 |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 1,900,000 | $41.69M | 2.9% | $24.51 | 0.0% | COM | 35104E100 |
| NVCR | NOVOCURE LTD | 550,000 | $41.29M | 2.9% | $100.38 | 0.0% | ORD SHS | G6674U108 |
| IMVT | IMMUNOVANT INC | 4,775,000 | $40.68M | 2.9% | $8.26 | 0.0% | COM | 45258J102 |
| — | CHINOOK THERAPEUTICS INC | 2,420,502 | $39.48M | 2.8% | $16.31 | — | COM | 16961L106 |
| KURA | KURA ONCOLOGY INC | 2,550,000 | $35.7M | 2.5% | $16.20 | 0.0% | COM | 50127T109 |
| — | DICE THERAPEUTICS INC | 1,341,004 | $33.94M | 2.4% | $25.31 | — | COM | 23345J104 |
| — | JOUNCE THERAPEUTICS INC | 4,000,000 | $33.4M | 2.4% | $8.35 | — | COM | 481116101 |
| ESPR | ESPERION THERAPEUTICS INC NE | 5,641,668 | $28.21M | 2.0% | $8.01 | 0.0% | COM | 29664W105 |
| DYN | DYNE THERAPEUTICS INC | 2,292,250 | $27.25M | 1.9% | $14.05 | 0.0% | COM | 26818M108 |
| VRDN | VIRIDIAN THERAPEUTICS INC | 1,336,690 | $26.43M | 1.9% | $18.63 | 0.0% | COM | 92790C104 |
| FATE | FATE THERAPEUTICS INC | 418,037 | $24.46M | 1.7% | $56.68 | 0.0% | COM | 31189P102 |
| RNAM | AVIDITY BIOSCIENCES INC | 1,000,000 | $23.77M | 1.7% | $23.88 | 0.0% | COM | 05370A108 |
| ACAD | ACADIA PHARMACEUTICALS INC | 1,000,000 | $23.34M | 1.6% | — | — | Call | 004225108 |
| — | GRITSTONE BIO INC | 1,771,801 | $22.79M | 1.6% | $12.86 | — | COM | 39868T105 |
| SLN | SILENCE THERAPEUTICS PLC | 950,798 | $22.71M | 1.6% | $23.89 | — | ADS | 82686Q101 |
| — | TRICIDA INC | 2,335,143 | $22.32M | 1.6% | $9.56 | — | COM | 89610F101 |
| — | MAGENTA THERAPEUTICS INC | 4,870,000 | $21.57M | 1.5% | $4.43 | — | COM | 55910K108 |
| — | SAGE THERAPEUTICS INC | 500,000 | $21.27M | 1.5% | $42.54 | — | COM | 78667J108 |
| — | PASSAGE BIO INC | 3,216,997 | $20.43M | 1.4% | $6.35 | — | COM | 702712100 |
| KALV | KALVISTA PHARMACEUTICALS INC | 1,500,000 | $19.84M | 1.4% | $15.92 | 0.0% | COM | 483497103 |
| NKTX | NKARTA INC | 1,264,426 | $19.41M | 1.4% | $17.15 | 0.0% | COM | 65487U108 |
| — | VERVE THERAPEUTICS INC | 500,000 | $18.43M | 1.3% | $36.87 | — | COM | 92539P101 |
| — | KARUNA THERAPEUTICS INC | 130,200 | $17.06M | 1.2% | $131.00 | — | COM | 48576A100 |
| — | SAGE THERAPEUTICS INC | 400,000 | $17.02M | 1.2% | $42.54 | — | Call | 78667J108 |
| TNYA | TENAYA THERAPEUTICS INC | 762,317 | $14.45M | 1.0% | $21.79 | 0.0% | COM | 87990A106 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 421,660 | $14.42M | 1.0% | $31.61 | 0.0% | COM | 74366E102 |
| FULC | FULCRUM THERAPEUTICS INC | 750,000 | $13.27M | 0.9% | $19.81 | 0.0% | COM | 359616109 |
| — | SIERRA ONCOLOGY INC | 607,600 | $13.21M | 0.9% | $21.74 | — | COM NEW | 82640U404 |
| ABOS | ACUMEN PHARMACEUTICALS INC | 1,933,040 | $13.07M | 0.9% | $10.99 | 0.0% | COM | 00509G209 |
| — | ATARA BIOTHERAPEUTICS INC | 750,000 | $11.82M | 0.8% | $15.76 | — | COM | 046513107 |
| GHRS | GH RESEARCH PLC | 499,400 | $11.65M | 0.8% | $21.97 | 0.0% | ORDINARY SHARES | G3855L106 |
| ASND | ASCENDIS PHARMA A/S | 80,000 | $10.76M | 0.8% | $134.53 | — | SPONSORED ADR | 04351P101 |
| ATYR | ATYR PHARMA INC | 1,100,000 | $8.217M | 0.6% | $8.35 | 0.0% | COM NEW | 002120202 |
| VNDA | VANDA PHARMACEUTICALS INC | 500,000 | $7.845M | 0.6% | $17.43 | 0.0% | Call | 921659108 |
| VNDA | VANDA PHARMACEUTICALS INC | 500,000 | $7.845M | 0.6% | $17.43 | 0.0% | COM | 921659108 |
| — | ASSEMBLY BIOSCIENCES INC | 3,000,000 | $6.99M | 0.5% | $2.33 | — | COM | 045396108 |
| — | NEKTAR THERAPEUTICS | 500,000 | $6.755M | 0.5% | — | — | Put | 640268108 |
| BBIO | BRIDGEBIO PHARMA INC | 400,000 | $6.672M | 0.5% | — | — | Call | 10806X102 |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 400,000 | $4.504M | 0.3% | $11.26 | — | SPONSORED ADS | 152309100 |
| — | AVROBIO INC | 1,050,132 | $4.043M | 0.3% | $3.85 | — | COM | 05455M100 |
| IPSC | CENTURY THERAPEUTICS INC | 250,000 | $3.965M | 0.3% | $18.79 | 0.0% | COM | 15673T100 |
| — | CONNECT BIOPHARMA HLDGS LTD | 647,057 | $3.332M | 0.2% | $5.15 | — | ADS | 207523101 |
| — | ONCORUS INC | 600,000 | $3.162M | 0.2% | $5.27 | — | COM | 68236R103 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 11,700 | $1.984M | 0.1% | — | — | Put | 02043Q107 |
| RFL | RAFAEL HLDGS INC | 285,714 | $1.457M | 0.1% | $13.45 | 0.0% | COM CL B | 75062E106 |