ACHAOGEN INC

CUSIP: 004449104 Class: COM

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 80,000 Value ($000) $1,041 Avg Close — Range —
Q1 2016
Shares 255,000 Value ($000) $704 Avg Close — Range —