ACHIEVE LIFE SCIENCE INC

CUSIP: 004468104 Class: COM

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 184,737 Value ($000) $235 Avg Close — Range —
Q4 2017
Shares 162,737 Value ($000) $219 Avg Close — Range —
Q3 2017
Shares 98,137 Value ($000) $199 Avg Close — Range —