ACTUATE THERAPEUTICS INC

Ticker: ACTU CUSIP: 005083100 Class: Common Stock

ROYAL BANK OF CANADA's Holding History (CIK: 0001000275)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 35,263 Value ($000) $215 Avg Close $6.87 Range $5.61 - $8.49

Q3 2025

Shares 12,954 Value ($000) $86 Avg Close $7.25 Range $5.47 - $9.22

Q2 2025

Shares 1,327 Value ($000) $8 Avg Close $8.74 Range $5.50 - $11.99

Q1 2025

Shares 18,538 Value ($000) $126 Avg Close $8.03 Range $6.02 - $11.73

Q4 2024

Shares 302 Value ($000) $2 Avg Close $8.16 Range $6.27 - $10.09

Q3 2024

Shares 35,300 Value ($000) $263 Avg Close $7.92 Range $5.51 - $10.16

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	35,263	$215	$6.87	$5.61 - $8.49
Q3 2025	12,954	$86	$7.25	$5.47 - $9.22
Q2 2025	1,327	$8	$8.74	$5.50 - $11.99
Q1 2025	18,538	$126	$8.03	$6.02 - $11.73
Q4 2024	302	$2	$8.16	$6.27 - $10.09
Q3 2024	35,300	$263	$7.92	$5.51 - $10.16