SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

FRED ALGER MANAGEMENT, LLC's Holding History (CIK: 0000003520)

Note: Option positions (PUT/CALL) are excluded.

Q1 2024

Shares 18,158 Value ($000) $689 Avg Close $28.97 Range $18.54 - $47.97

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2024	18,158	$689	$28.97	$18.54 - $47.97