SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

MEEDER ASSET MANAGEMENT INC's Holding History (CIK: 0000809443)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 181 Value ($000) $6 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 216 Value ($000) $4 Avg Close $16.31 Range $14.00 - $18.30

Q2 2025

Shares 170 Value ($000) $3 Avg Close $14.80 Range $10.91 - $19.20

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	181	$6	$26.13	$15.86 - $35.31
Q3 2025	216	$4	$16.31	$14.00 - $18.30
Q2 2025	170	$3	$14.80	$10.91 - $19.20