SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

UBS ASSET MANAGEMENT AMERICAS INC's Holding History (CIK: 0000861177)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 62,216 Value ($000) $2,038 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 39,498 Value ($000) $662 Avg Close $16.31 Range $14.00 - $18.30

Q2 2025

Shares 85,702 Value ($000) $1,283 Avg Close $14.80 Range $10.91 - $19.20

Q1 2025

Shares 52,138 Value ($000) $841 Avg Close $20.81 Range $16.13 - $26.01

Q4 2024

Shares 48,981 Value ($000) $1,140 Avg Close $29.32 Range $22.37 - $40.26

Q3 2024

Shares 26,441 Value ($000) $778 Avg Close $27.85 Range $23.00 - $32.41

Q2 2024

Shares 30,121 Value ($000) $708 Avg Close $33.73 Range $22.19 - $40.84

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	62,216	$2,038	$26.13	$15.86 - $35.31
Q3 2025	39,498	$662	$16.31	$14.00 - $18.30
Q2 2025	85,702	$1,283	$14.80	$10.91 - $19.20
Q1 2025	52,138	$841	$20.81	$16.13 - $26.01
Q4 2024	48,981	$1,140	$29.32	$22.37 - $40.26
Q3 2024	26,441	$778	$27.85	$23.00 - $32.41
Q2 2024	30,121	$708	$33.73	$22.19 - $40.84