SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

SOROS FUND MANAGEMENT LLC's Holding History (CIK: 0001029160)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 125,000 Value ($000) $2,017 Avg Close $20.81 Range $16.13 - $26.01

Q4 2024

Shares 250,000 Value ($000) $5,820 Avg Close $29.32 Range $22.37 - $40.26

Q3 2024

Shares 145,000 Value ($000) $4,264 Avg Close $27.85 Range $23.00 - $32.41

Q2 2024

Shares 145,000 Value ($000) $3,409 Avg Close $33.73 Range $22.19 - $40.84

Q1 2024

Shares 30,038 Value ($000) $1,139 Avg Close $28.97 Range $18.54 - $47.97

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	125,000	$2,017	$20.81	$16.13 - $26.01
Q4 2024	250,000	$5,820	$29.32	$22.37 - $40.26
Q3 2024	145,000	$4,264	$27.85	$23.00 - $32.41
Q2 2024	145,000	$3,409	$33.73	$22.19 - $40.84
Q1 2024	30,038	$1,139	$28.97	$18.54 - $47.97