SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

VICTORY CAPITAL MANAGEMENT INC's Holding History (CIK: 0001040188)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 146,079 Value ($000) $4,786 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 326,081 Value ($000) $5,465 Avg Close $16.31 Range $14.00 - $18.30

Q2 2025

Shares 354,116 Value ($000) $5,301 Avg Close $14.80 Range $10.91 - $19.20

Q1 2025

Shares 251,846 Value ($000) $4,064 Avg Close $20.81 Range $16.13 - $26.01

Q4 2024

Shares 268,076 Value ($000) $6,241 Avg Close $29.32 Range $22.37 - $40.26

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	146,079	$4,786	$26.13	$15.86 - $35.31
Q3 2025	326,081	$5,465	$16.31	$14.00 - $18.30
Q2 2025	354,116	$5,301	$14.80	$10.91 - $19.20
Q1 2025	251,846	$4,064	$20.81	$16.13 - $26.01
Q4 2024	268,076	$6,241	$29.32	$22.37 - $40.26