SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

Voya Investment Management LLC's Holding History (CIK: 0001068837)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 27,277 Value ($000) $894 Avg Close $26.13 Range $15.86 - $35.31

Q2 2025

Shares 13,589 Value ($000) $203 Avg Close $14.80 Range $10.91 - $19.20

Q1 2025

Shares 10,348 Value ($000) $167 Avg Close $20.81 Range $16.13 - $26.01

Q4 2024

Shares 10,495 Value ($000) $244 Avg Close $29.32 Range $22.37 - $40.26

Q3 2024

Shares 11,351 Value ($000) $334 Avg Close $27.85 Range $23.00 - $32.41

Q2 2024

Shares 11,607 Value ($000) $273 Avg Close $33.73 Range $22.19 - $40.84

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	27,277	$894	$26.13	$15.86 - $35.31
Q2 2025	13,589	$203	$14.80	$10.91 - $19.20
Q1 2025	10,348	$167	$20.81	$16.13 - $26.01
Q4 2024	10,495	$244	$29.32	$22.37 - $40.26
Q3 2024	11,351	$334	$27.85	$23.00 - $32.41
Q2 2024	11,607	$273	$33.73	$22.19 - $40.84