SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

SG Americas Securities, LLC's Holding History (CIK: 0001313360)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 23,343 Value ($000) $1 Avg Close $26.13 Range $15.86 - $35.31

Q1 2025

Shares 7,122 Value ($000) $0 Avg Close $20.81 Range $16.13 - $26.01

Q3 2024

Shares 12,589 Value ($000) $0 Avg Close $27.85 Range $23.00 - $32.41

Q2 2024

Shares 5,545 Value ($000) $0 Avg Close $33.73 Range $22.19 - $40.84

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	23,343	$1	$26.13	$15.86 - $35.31
Q1 2025	7,122	$0	$20.81	$16.13 - $26.01
Q3 2024	12,589	$0	$27.85	$23.00 - $32.41
Q2 2024	5,545	$0	$33.73	$22.19 - $40.84