SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

Blackstone Inc.'s Holding History (CIK: 0001393818)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 500,998 Value ($000) $16,413 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 500,998 Value ($000) $8,397 Avg Close $16.31 Range $14.00 - $18.30

Q2 2025

Shares 489,248 Value ($000) $7,324 Avg Close $14.80 Range $10.91 - $19.20

Q1 2025

Shares 489,248 Value ($000) $7,894 Avg Close $20.81 Range $16.13 - $26.01

Q4 2024

Shares 449,201 Value ($000) $10,457 Avg Close $29.32 Range $22.37 - $40.26

Q3 2024

Shares 292,995 Value ($000) $8,617 Avg Close $27.85 Range $23.00 - $32.41

Q2 2024

Shares 292,995 Value ($000) $6,888 Avg Close $33.73 Range $22.19 - $40.84

Q1 2024

Shares 19,991 Value ($000) $758 Avg Close $28.97 Range $18.54 - $47.97

Q4 2023

Shares 19,991 Value ($000) $430 Avg Close $13.78 Range $8.43 - $22.66

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	500,998	$16,413	$26.13	$15.86 - $35.31
Q3 2025	500,998	$8,397	$16.31	$14.00 - $18.30
Q2 2025	489,248	$7,324	$14.80	$10.91 - $19.20
Q1 2025	489,248	$7,894	$20.81	$16.13 - $26.01
Q4 2024	449,201	$10,457	$29.32	$22.37 - $40.26
Q3 2024	292,995	$8,617	$27.85	$23.00 - $32.41
Q2 2024	292,995	$6,888	$33.73	$22.19 - $40.84
Q1 2024	19,991	$758	$28.97	$18.54 - $47.97
Q4 2023	19,991	$430	$13.78	$8.43 - $22.66