SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

UBS Group AG's Holding History (CIK: 0001610520)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 680,566 Value ($000) $22,295 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 385,589 Value ($000) $6,462 Avg Close $16.31 Range $14.00 - $18.30

Q2 2025

Shares 462,863 Value ($000) $6,929 Avg Close $14.80 Range $10.91 - $19.20

Q1 2025

Shares 552,243 Value ($000) $8,910 Avg Close $20.81 Range $16.13 - $26.01

Q4 2024

Shares 392,197 Value ($000) $9,130 Avg Close $29.32 Range $22.37 - $40.26

Q3 2024

Shares 57,838 Value ($000) $1,701 Avg Close $27.85 Range $23.00 - $32.41

Q2 2024

Shares 44,504 Value ($000) $1,046 Avg Close $33.73 Range $22.19 - $40.84

Q1 2024

Shares 2,601 Value ($000) $99 Avg Close $28.97 Range $18.54 - $47.97

Q4 2023

Shares 3,726 Value ($000) $80 Avg Close $13.78 Range $8.43 - $22.66

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	680,566	$22,295	$26.13	$15.86 - $35.31
Q3 2025	385,589	$6,462	$16.31	$14.00 - $18.30
Q2 2025	462,863	$6,929	$14.80	$10.91 - $19.20
Q1 2025	552,243	$8,910	$20.81	$16.13 - $26.01
Q4 2024	392,197	$9,130	$29.32	$22.37 - $40.26
Q3 2024	57,838	$1,701	$27.85	$23.00 - $32.41
Q2 2024	44,504	$1,046	$33.73	$22.19 - $40.84
Q1 2024	2,601	$99	$28.97	$18.54 - $47.97
Q4 2023	3,726	$80	$13.78	$8.43 - $22.66