SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

Avoro Capital Advisors LLC's Holding History (CIK: 0001633313)

Note: Option positions (PUT/CALL) are excluded.

Q3 2024

Shares 598,600 Value ($000) $17,605 Avg Close $27.85 Range $23.00 - $32.41

Q2 2024

Shares 1,839,138 Value ($000) $43,238 Avg Close $33.73 Range $22.19 - $40.84

Q1 2024

Shares 1,839,138 Value ($000) $69,759 Avg Close $28.97 Range $18.54 - $47.97

Q4 2023

Shares 1,839,138 Value ($000) $39,578 Avg Close $13.78 Range $8.43 - $22.66

Q3 2023

Shares 11,458 Value ($000) $140 Avg Close $13.22 Range $9.53 - $18.00

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2024	598,600	$17,605	$27.85	$23.00 - $32.41
Q2 2024	1,839,138	$43,238	$33.73	$22.19 - $40.84
Q1 2024	1,839,138	$69,759	$28.97	$18.54 - $47.97
Q4 2023	1,839,138	$39,578	$13.78	$8.43 - $22.66
Q3 2023	11,458	$140	$13.22	$9.53 - $18.00