SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

Parkman Healthcare Partners LLC's Holding History (CIK: 0001777015)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 124,485 Value ($000) $4,078 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 200,753 Value ($000) $3,365 Avg Close $16.31 Range $14.00 - $18.30

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	124,485	$4,078	$26.13	$15.86 - $35.31
Q3 2025	200,753	$3,365	$16.31	$14.00 - $18.30