SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

AlphaQuest LLC's Holding History (CIK: 0001883897)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,538 Value ($000) $116 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 66,163 Value ($000) $1,109 Avg Close $16.31 Range $14.00 - $18.30

Q2 2025

Shares 4,174 Value ($000) $62 Avg Close $14.80 Range $10.91 - $19.20

Q1 2025

Shares 3,191 Value ($000) $51 Avg Close $20.81 Range $16.13 - $26.01

Q4 2024

Shares 2,198 Value ($000) $51 Avg Close $29.32 Range $22.37 - $40.26

Q3 2024

Shares 5,654 Value ($000) $166 Avg Close $27.85 Range $23.00 - $32.41

Q2 2024

Shares 1,523 Value ($000) $36 Avg Close $33.73 Range $22.19 - $40.84

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,538	$116	$26.13	$15.86 - $35.31
Q3 2025	66,163	$1,109	$16.31	$14.00 - $18.30
Q2 2025	4,174	$62	$14.80	$10.91 - $19.20
Q1 2025	3,191	$51	$20.81	$16.13 - $26.01
Q4 2024	2,198	$51	$29.32	$22.37 - $40.26
Q3 2024	5,654	$166	$27.85	$23.00 - $32.41
Q2 2024	1,523	$36	$33.73	$22.19 - $40.84