SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

SEVEN GRAND MANAGERS, LLC's Holding History (CIK: 0001909126)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 100,000 Value ($000) $3,276 Avg Close $26.13 Range $15.86 - $35.31

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	100,000	$3,276	$26.13	$15.86 - $35.31