SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

Susquehanna Portfolio Strategies, LLC's Holding History (CIK: 0001996449)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 53,101 Value ($000) $1,740 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 21,739 Value ($000) $364 Avg Close $16.31 Range $14.00 - $18.30

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	53,101	$1,740	$26.13	$15.86 - $35.31
Q3 2025	21,739	$364	$16.31	$14.00 - $18.30