SPYRE THERAPEUTICS INC

Ticker: SYRE CUSIP: 00773J202 Class: Common Stock

Universal- Beteiligungs- und Servicegesellschaft mbH's Holding History (CIK: 0002057170)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 171,211 Value ($000) $5,609 Avg Close $26.13 Range $15.86 - $35.31

Q3 2025

Shares 110,456 Value ($000) $1,851 Avg Close $16.31 Range $14.00 - $18.30

Q2 2025

Shares 109,284 Value ($000) $1,636 Avg Close $14.80 Range $10.91 - $19.20

Q1 2025

Shares 120,321 Value ($000) $1,941 Avg Close $20.81 Range $16.13 - $26.01

Q4 2024

Shares 122,153 Value ($000) $2,844 Avg Close $29.32 Range $22.37 - $40.26

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	171,211	$5,609	$26.13	$15.86 - $35.31
Q3 2025	110,456	$1,851	$16.31	$14.00 - $18.30
Q2 2025	109,284	$1,636	$14.80	$10.91 - $19.20
Q1 2025	120,321	$1,941	$20.81	$16.13 - $26.01
Q4 2024	122,153	$2,844	$29.32	$22.37 - $40.26