JADE BIOSCIENCES INC

Ticker: JBIO CUSIP: 008064206 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,671,083 Value ($000) $56,645 Avg Close $11.73 Range $8.16 - $17.71

Q3 2025

Shares 1,062,326 Value ($000) $9,168 Avg Close $8.17 Range $6.67 - $11.33

Q2 2025

Shares 1,062,326 Value ($000) $10,613 Avg Close $33.31 Range $6.57 - $97.54

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,671,083	$56,645	$11.73	$8.16 - $17.71
Q3 2025	1,062,326	$9,168	$8.17	$6.67 - $11.33
Q2 2025	1,062,326	$10,613	$33.31	$6.57 - $97.54