AERPIO PHARMACEUTICALS INC

CUSIP: 00810B105 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 1,131,819 Value ($000) $1,924 Avg Close — Range —
Q3 2018
Shares 1,131,819 Value ($000) $3,497 Avg Close — Range —
Q2 2018
Shares 1,103,554 Value ($000) $4,580 Avg Close — Range —