AGENUS INC

Ticker: AGEN CUSIP: 00847G804 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 117,117 Value ($000) $368 Avg Close $3.98 Range $3.01 - $4.69

Q3 2025

Shares 102,353 Value ($000) $394 Avg Close $5.01 Range $3.76 - $7.34

Q3 2024

Shares 19,308 Value ($000) $106 Avg Close $7.49 Range $4.41 - $18.74

Q2 2024

Shares 29,639 Value ($000) $496 Avg Close $12.08 Range $4.78 - $19.69

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	117,117	$368	$3.98	$3.01 - $4.69
Q3 2025	102,353	$394	$5.01	$3.76 - $7.34
Q3 2024	19,308	$106	$7.49	$4.41 - $18.74
Q2 2024	29,639	$496	$12.08	$4.78 - $19.69