AGILE THERAPEUTICS INC

CUSIP: 00847L100 Class: Common Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 15,000 Value ($000) $85 Avg Close — Range —
Q4 2015
Shares 300,000 Value ($000) $2,928 Avg Close — Range —
Q3 2015
Shares 385,000 Value ($000) $2,595 Avg Close — Range —
Q2 2015
Shares 55,000 Value ($000) $472 Avg Close — Range —