AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

AMERICAN CENTURY COMPANIES INC's Holding History (CIK: 0000748054)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 151,486 Value ($000) $4,123 Avg Close $35.08 Range $22.24 - $46.00

Q3 2025

Shares 145,121 Value ($000) $5,825 Avg Close $37.61 Range $26.75 - $41.74

Q2 2025

Shares 127,647 Value ($000) $4,246 Avg Close $30.31 Range $23.42 - $36.39

Q1 2025

Shares 114,947 Value ($000) $3,368 Avg Close $33.17 Range $28.31 - $36.17

Q4 2024

Shares 104,837 Value ($000) $3,445 Avg Close $46.98 Range $32.31 - $62.58

Q3 2024

Shares 114,220 Value ($000) $5,075 Avg Close $45.42 Range $40.80 - $53.29

Q2 2024

Shares 94,486 Value ($000) $4,074 Avg Close $36.09 Range $27.14 - $49.06

Q1 2024

Shares 80,616 Value ($000) $2,357 Avg Close $26.78 Range $20.96 - $35.50

Q4 2023

Shares 62,352 Value ($000) $1,389 Avg Close $22.41 Range $19.80 - $24.89

Q3 2023

Shares 46,153 Value ($000) $1,142 Avg Close $26.45 Range $24.04 - $28.65

Q2 2023

Shares 35,892 Value ($000) $1,016 Avg Close $24.88 Range $21.09 - $29.23

Q1 2023

Shares 25,259 Value ($000) $570 Avg Close $26.56 Range $21.07 - $31.56

Q4 2022

Shares 20,543 Value ($000) $577 Avg Close $28.18 Range $24.70 - $31.87

Q3 2022

Shares 8,592 Value ($000) $243 Avg Close $26.82 Range $19.43 - $34.76

Q3 2019

Shares 46,472 Value ($000) $1,506 Avg Close $41.40 Range $31.46 - $51.09

Q2 2019

Shares 119,526 Value ($000) $5,962 Avg Close $53.45 Range $45.43 - $68.89

Q1 2019

Shares 111,526 Value ($000) $7,521 Avg Close $58.25 Range $44.37 - $68.94

Q4 2018

Shares 97,366 Value ($000) $4,490 Avg Close $61.72 Range $41.63 - $79.17

Q4 2015

Shares 83,316 Value ($000) $5,409 Avg Close $65.59 Range $48.00 - $81.77

Q3 2015

Shares 174,286 Value ($000) $12,303 Avg Close $97.74 Range $67.52 - $120.96

Q2 2015

Shares 174,296 Value ($000) $19,371 Avg Close $107.71 Range $90.58 - $126.35

Q1 2015

Shares 10,222 Value ($000) $964 Avg Close $112.06 Range $88.03 - $138.85

Q4 2014

Shares 10,293 Value ($000) $1,153 Avg Close $89.28 Range $58.55 - $124.39

Q3 2014

Shares 9,351 Value ($000) $574 Avg Close $43.10 Range $33.01 - $69.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	151,486	$4,123	$35.08	$22.24 - $46.00
Q3 2025	145,121	$5,825	$37.61	$26.75 - $41.74
Q2 2025	127,647	$4,246	$30.31	$23.42 - $36.39
Q1 2025	114,947	$3,368	$33.17	$28.31 - $36.17
Q4 2024	104,837	$3,445	$46.98	$32.31 - $62.58
Q3 2024	114,220	$5,075	$45.42	$40.80 - $53.29
Q2 2024	94,486	$4,074	$36.09	$27.14 - $49.06
Q1 2024	80,616	$2,357	$26.78	$20.96 - $35.50
Q4 2023	62,352	$1,389	$22.41	$19.80 - $24.89
Q3 2023	46,153	$1,142	$26.45	$24.04 - $28.65
Q2 2023	35,892	$1,016	$24.88	$21.09 - $29.23
Q1 2023	25,259	$570	$26.56	$21.07 - $31.56
Q4 2022	20,543	$577	$28.18	$24.70 - $31.87
Q3 2022	8,592	$243	$26.82	$19.43 - $34.76
Q3 2019	46,472	$1,506	$41.40	$31.46 - $51.09
Q2 2019	119,526	$5,962	$53.45	$45.43 - $68.89
Q1 2019	111,526	$7,521	$58.25	$44.37 - $68.94
Q4 2018	97,366	$4,490	$61.72	$41.63 - $79.17
Q4 2015	83,316	$5,409	$65.59	$48.00 - $81.77
Q3 2015	174,286	$12,303	$97.74	$67.52 - $120.96
Q2 2015	174,296	$19,371	$107.71	$90.58 - $126.35
Q1 2015	10,222	$964	$112.06	$88.03 - $138.85
Q4 2014	10,293	$1,153	$89.28	$58.55 - $124.39
Q3 2014	9,351	$574	$43.10	$33.01 - $69.50