AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

TOCQUEVILLE ASSET MANAGEMENT L.P.'s Holding History (CIK: 0000883961)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016

Shares 13,600 Value ($000) $570 Avg Close $49.39 Range $39.36 - $66.74

Q1 2016

Shares 16,125 Value ($000) $655 Avg Close $42.75 Range $33.50 - $66.87

Q4 2015

Shares 19,400 Value ($000) $1,259 Avg Close $65.59 Range $48.00 - $81.77

Q3 2015

Shares 19,600 Value ($000) $1,384 Avg Close $97.74 Range $67.52 - $120.96

Q2 2015

Shares 12,875 Value ($000) $1,431 Avg Close $107.71 Range $90.58 - $126.35

Q1 2015

Shares 8,900 Value ($000) $839 Avg Close $112.06 Range $88.03 - $138.85

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2016	13,600	$570	$49.39	$39.36 - $66.74
Q1 2016	16,125	$655	$42.75	$33.50 - $66.87
Q4 2015	19,400	$1,259	$65.59	$48.00 - $81.77
Q3 2015	19,600	$1,384	$97.74	$67.52 - $120.96
Q2 2015	12,875	$1,431	$107.71	$90.58 - $126.35
Q1 2015	8,900	$839	$112.06	$88.03 - $138.85