AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

GILDER GAGNON HOWE & CO LLC's Holding History (CIK: 0000902464)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015

Shares 367,726 Value ($000) $23,873 Avg Close $65.59 Range $48.00 - $81.77

Q3 2015

Shares 411,653 Value ($000) $29,059 Avg Close $97.74 Range $67.52 - $120.96

Q2 2015

Shares 415,460 Value ($000) $46,174 Avg Close $107.71 Range $90.58 - $126.35

Q1 2015

Shares 72,082 Value ($000) $6,797 Avg Close $112.06 Range $88.03 - $138.85

Q4 2014

Shares 103,316 Value ($000) $11,576 Avg Close $89.28 Range $58.55 - $124.39

Q3 2014

Shares 10,023 Value ($000) $615 Avg Close $43.10 Range $33.01 - $69.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2015	367,726	$23,873	$65.59	$48.00 - $81.77
Q3 2015	411,653	$29,059	$97.74	$67.52 - $120.96
Q2 2015	415,460	$46,174	$107.71	$90.58 - $126.35
Q1 2015	72,082	$6,797	$112.06	$88.03 - $138.85
Q4 2014	103,316	$11,576	$89.28	$58.55 - $124.39
Q3 2014	10,023	$615	$43.10	$33.01 - $69.50