AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

GREAT LAKES ADVISORS, LLC's Holding History (CIK: 0001078013)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021

Shares 389,071 Value ($000) $21,442 Avg Close $55.92 Range $51.07 - $62.16

Q1 2021

Shares 391,359 Value ($000) $20,210 Avg Close $49.52 Range $42.87 - $58.93

Q4 2020

Shares 366,699 Value ($000) $15,889 Avg Close $39.54 Range $32.47 - $49.98

Q3 2020

Shares 386,890 Value ($000) $13,541 Avg Close $43.83 Range $33.45 - $56.75

Q2 2020

Shares 323,963 Value ($000) $17,326 Avg Close $46.30 Range $34.08 - $54.53

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2021	389,071	$21,442	$55.92	$51.07 - $62.16
Q1 2021	391,359	$20,210	$49.52	$42.87 - $58.93
Q4 2020	366,699	$15,889	$39.54	$32.47 - $49.98
Q3 2020	386,890	$13,541	$43.83	$33.45 - $56.75
Q2 2020	323,963	$17,326	$46.30	$34.08 - $54.53