AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

HighVista Strategies LLC's Holding History (CIK: 0001335325)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 147,662 Value ($000) $4,019 Avg Close $35.08 Range $22.24 - $46.00

Q3 2025

Shares 195,298 Value ($000) $7,839 Avg Close $37.61 Range $26.75 - $41.74

Q2 2025

Shares 70,127 Value ($000) $2,332 Avg Close $30.31 Range $23.42 - $36.39

Q1 2025

Shares 44,105 Value ($000) $1,292 Avg Close $33.17 Range $28.31 - $36.17

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	147,662	$4,019	$35.08	$22.24 - $46.00
Q3 2025	195,298	$7,839	$37.61	$26.75 - $41.74
Q2 2025	70,127	$2,332	$30.31	$23.42 - $36.39
Q1 2025	44,105	$1,292	$33.17	$28.31 - $36.17