AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015

Shares 9,900 Value ($000) $1,100 Avg Close $107.71 Range $90.58 - $126.35

Q1 2015

Shares 17,600 Value ($000) $1,660 Avg Close $112.06 Range $88.03 - $138.85

Q4 2014

Shares 17,600 Value ($000) $1,972 Avg Close $89.28 Range $58.55 - $124.39

Q3 2014

Shares 17,600 Value ($000) $1,080 Avg Close $43.10 Range $33.01 - $69.50

Q3 2013

Shares 70,000 Value ($000) $1,957 Avg Close $27.61 Range $22.34 - $33.45

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2015	9,900	$1,100	$107.71	$90.58 - $126.35
Q1 2015	17,600	$1,660	$112.06	$88.03 - $138.85
Q4 2014	17,600	$1,972	$89.28	$58.55 - $124.39
Q3 2014	17,600	$1,080	$43.10	$33.01 - $69.50
Q3 2013	70,000	$1,957	$27.61	$22.34 - $33.45