AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

PFM Health Sciences, LP's Holding History (CIK: 0001442756)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018

Shares 614,506 Value ($000) $51,760 Avg Close $87.20 Range $72.14 - $99.82

Q1 2018

Shares 677,091 Value ($000) $55,373 Avg Close $77.29 Range $56.50 - $87.00

Q3 2014

Shares 108,241 Value ($000) $6,641 Avg Close $43.10 Range $33.01 - $69.50

Q3 2013

Shares 206,829 Value ($000) $5,783 Avg Close $27.61 Range $22.34 - $33.45

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2018	614,506	$51,760	$87.20	$72.14 - $99.82
Q1 2018	677,091	$55,373	$77.29	$56.50 - $87.00
Q3 2014	108,241	$6,641	$43.10	$33.01 - $69.50
Q3 2013	206,829	$5,783	$27.61	$22.34 - $33.45