AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

Polar Capital Holdings Plc's Holding History (CIK: 0001837309)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 1,002,036 Value ($000) $29,360 Avg Close $33.17 Range $28.31 - $36.17

Q4 2024

Shares 627,036 Value ($000) $20,604 Avg Close $46.98 Range $32.31 - $62.58

Q3 2024

Shares 1,002,036 Value ($000) $44,520 Avg Close $45.42 Range $40.80 - $53.29

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	1,002,036	$29,360	$33.17	$28.31 - $36.17
Q4 2024	627,036	$20,604	$46.98	$32.31 - $62.58
Q3 2024	1,002,036	$44,520	$45.42	$40.80 - $53.29