AGIOS PHARMACEUTICALS INC

Ticker: AGIO CUSIP: 00847X104 Class: Common Stock

Paradigm Biocapital Advisors LP's Holding History (CIK: 0001855655)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 2,673,555 Value ($000) $107,316 Avg Close $37.61 Range $26.75 - $41.74

Q2 2025

Shares 1,142,511 Value ($000) $38,000 Avg Close $30.31 Range $23.42 - $36.39

Q4 2024

Shares 276,439 Value ($000) $9,084 Avg Close $46.98 Range $32.31 - $62.58

Q1 2024

Shares 400,000 Value ($000) $11,696 Avg Close $26.78 Range $20.96 - $35.50

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	2,673,555	$107,316	$37.61	$26.75 - $41.74
Q2 2025	1,142,511	$38,000	$30.31	$23.42 - $36.39
Q4 2024	276,439	$9,084	$46.98	$32.31 - $62.58
Q1 2024	400,000	$11,696	$26.78	$20.96 - $35.50