ALDER BIOPHARMACEUTICALS INC

CUSIP: 014339105 Class: COM

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018

Shares 101,500 Value ($000) $1,690 Avg Close — Range —

Q2 2018

Shares 434,800 Value ($000) $6,870 Avg Close — Range —

Q1 2018

Shares 322,300 Value ($000) $4,093 Avg Close — Range —

Q1 2016

Shares 26,600 Value ($000) $651 Avg Close — Range —

Q2 2015

Shares 118,300 Value ($000) $6,266 Avg Close — Range —

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2018	101,500	$1,690	—	—
Q2 2018	434,800	$6,870	—	—
Q1 2018	322,300	$4,093	—	—
Q1 2016	26,600	$651	—	—
Q2 2015	118,300	$6,266	—	—