ALDER BIOPHARMACEUTICALS INC

CUSIP: 014339105 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 112,500 Value ($000) $3,687 Avg Close — Range —
Q1 2016
Shares 62,500 Value ($000) $1,531 Avg Close — Range —
Q4 2015
Shares 112,500 Value ($000) $3,716 Avg Close — Range —
Q3 2015
Shares 125,000 Value ($000) $4,095 Avg Close — Range —
Q2 2015
Shares 125,000 Value ($000) $6,621 Avg Close — Range —
Q1 2015
Shares 150,000 Value ($000) $4,329 Avg Close — Range —