ALEXION PHARMACEUTICALS INC

CUSIP: 015351109 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q4 2020
Shares 60,000 Value ($000) $9,374 Avg Close — Range —
Q1 2020
Shares 249,396 Value ($000) $22,393 Avg Close — Range —
Q4 2019
Shares 115,713 Value ($000) $12,514 Avg Close — Range —
Q3 2019
Shares 165,713 Value ($000) $16,230 Avg Close — Range —
Q2 2019
Shares 336,800 Value ($000) $44,114 Avg Close — Range —
Q1 2019
Shares 247,300 Value ($000) $33,430 Avg Close — Range —
Q4 2018
Shares 168,100 Value ($000) $16,366 Avg Close — Range —
Q3 2018
Shares 141,700 Value ($000) $19,698 Avg Close — Range —
Q2 2018
Shares 160,544 Value ($000) $19,932 Avg Close — Range —
Q1 2018
Shares 82,000 Value ($000) $9,140 Avg Close — Range —
Q4 2017
Shares 120,000 Value ($000) $14,351 Avg Close — Range —
Q2 2017
Shares 100,000 Value ($000) $12,167 Avg Close — Range —
Q4 2016
Shares 113,000 Value ($000) $13,826 Avg Close — Range —
Q3 2016
Shares 70,000 Value ($000) $8,578 Avg Close — Range —
Q1 2016
Shares 40,000 Value ($000) $5,569 Avg Close — Range —
Q4 2015
Shares 59,164 Value ($000) $11,286 Avg Close — Range —
Q3 2015
Shares 35,000 Value ($000) $5,474 Avg Close — Range —
Q1 2015
Shares 25,000 Value ($000) $4,333 Avg Close — Range —