ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

ROYAL BANK OF CANADA's Holding History (CIK: 0001000275)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 591,495 Value ($000) $235,207 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 436,758 Value ($000) $199,162 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 430,835 Value ($000) $140,491 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 337,231 Value ($000) $91,061 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 310,187 Value ($000) $72,991 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 411,066 Value ($000) $113,056 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 411,364 Value ($000) $99,962 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 374,424 Value ($000) $55,959 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 257,955 Value ($000) $49,375 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 244,106 Value ($000) $43,232 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 246,222 Value ($000) $46,768 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 216,159 Value ($000) $43,301 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 196,580 Value ($000) $46,718 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 66,016 Value ($000) $13,213 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 81,103 Value ($000) $11,830 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 22,595 Value ($000) $3,690 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 28,201 Value ($000) $4,783 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 24,592 Value ($000) $4,644 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 16,128 Value ($000) $2,734 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 16,199 Value ($000) $2,287 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 29,525 Value ($000) $3,837 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 19,563 Value ($000) $2,849 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 23,768 Value ($000) $3,520 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 22,911 Value ($000) $2,494 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 20,332 Value ($000) $2,342 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 36,114 Value ($000) $2,904 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 40,224 Value ($000) $2,918 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 13,686 Value ($000) $1,278 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 11,463 Value ($000) $835 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 10,145 Value ($000) $888 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 7,131 Value ($000) $703 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 5,465 Value ($000) $651 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 2,687 Value ($000) $341 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 1,763 Value ($000) $207 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 1,483 Value ($000) $118 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 5,360 Value ($000) $274 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 3,409 Value ($000) $128 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 57,680 Value ($000) $3,910 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 51,314 Value ($000) $2,847 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 31,487 Value ($000) $1,977 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 26,105 Value ($000) $2,457 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 12,221 Value ($000) $982 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 12,676 Value ($000) $1,519 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 17,453 Value ($000) $1,821 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 7,834 Value ($000) $759 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 24,164 Value ($000) $1,888 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 7,763 Value ($000) $490 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 1,256 Value ($000) $84 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 3,309 Value ($000) $214 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 5,219 Value ($000) $334 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 3,525 Value ($000) $109 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	591,495	$235,207	$442.56	$387.03 - $495.55
Q3 2025	436,758	$199,162	$407.20	$309.57 - $484.21
Q2 2025	430,835	$140,491	$276.71	$205.87 - $327.21
Q1 2025	337,231	$91,061	$257.00	$230.79 - $300.90
Q4 2024	310,187	$72,991	$262.99	$229.86 - $304.39
Q3 2024	411,066	$113,056	$260.36	$231.01 - $287.55
Q2 2024	411,364	$99,962	$157.87	$141.98 - $252.87
Q1 2024	374,424	$55,959	$166.82	$143.52 - $199.38
Q4 2023	257,955	$49,375	$170.34	$148.10 - $198.00
Q3 2023	244,106	$43,232	$191.12	$168.65 - $218.88
Q2 2023	246,222	$46,768	$198.26	$183.00 - $212.47
Q1 2023	216,159	$43,301	$210.20	$179.19 - $242.39
Q4 2022	196,580	$46,718	$213.29	$181.65 - $242.97
Q3 2022	66,016	$13,213	$190.74	$135.46 - $236.80
Q2 2022	81,103	$11,830	$141.87	$117.58 - $180.35
Q1 2022	22,595	$3,690	$152.35	$125.00 - $174.66
Q4 2021	28,201	$4,783	$185.86	$154.82 - $212.00
Q3 2021	24,592	$4,644	$187.58	$166.16 - $209.73
Q2 2021	16,128	$2,734	$146.46	$125.08 - $177.53
Q1 2021	16,199	$2,287	$150.49	$124.00 - $178.41
Q4 2020	29,525	$3,837	$133.53	$119.29 - $148.76
Q3 2020	19,563	$2,849	$142.10	$119.67 - $167.33
Q2 2020	23,768	$3,520	$134.81	$98.01 - $158.37
Q1 2020	22,911	$2,494	$115.43	$84.97 - $134.51
Q4 2019	20,332	$2,342	$99.70	$73.32 - $125.72
Q3 2019	36,114	$2,904	$79.11	$69.11 - $88.00
Q2 2019	40,224	$2,918	$76.72	$65.81 - $96.08
Q1 2019	13,686	$1,278	$83.64	$70.29 - $93.95
Q4 2018	11,463	$835	$76.92	$60.27 - $90.00
Q3 2018	10,145	$888	$100.59	$86.95 - $124.22
Q2 2018	7,131	$703	$99.19	$87.35 - $118.71
Q1 2018	5,465	$651	$128.92	$108.13 - $153.99
Q4 2017	2,687	$341	$125.65	$111.25 - $147.63
Q3 2017	1,763	$207	$85.36	$70.76 - $119.02
Q2 2017	1,483	$118	$63.91	$46.90 - $86.92
Q1 2017	5,360	$274	$46.22	$35.98 - $60.41
Q4 2016	3,409	$128	$41.87	$31.38 - $71.67
Q3 2016	57,680	$3,910	$70.55	$53.56 - $80.11
Q2 2016	51,314	$2,847	$63.00	$49.96 - $75.08
Q1 2016	31,487	$1,977	$66.49	$51.51 - $98.00
Q4 2015	26,105	$2,457	$92.72	$71.14 - $110.75
Q3 2015	12,221	$982	$111.10	$76.46 - $137.89
Q2 2015	12,676	$1,519	$119.50	$98.63 - $140.00
Q1 2015	17,453	$1,821	$101.34	$82.06 - $121.93
Q4 2014	7,834	$759	$92.65	$72.80 - $111.49
Q3 2014	24,164	$1,888	$64.51	$51.93 - $79.88
Q2 2014	7,763	$490	$59.44	$47.03 - $71.40
Q1 2014	1,256	$84	$77.42	$60.24 - $112.57
Q4 2013	3,309	$214	$59.65	$48.16 - $67.97
Q3 2013	5,219	$334	$49.85	$31.75 - $65.83
Q2 2013	3,525	$109	$26.61	$21.60 - $31.79