ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018

Shares 64,400 Value ($000) $5,636 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 375,400 Value ($000) $36,973 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 235,400 Value ($000) $28,036 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 8,100 Value ($000) $1,029 Avg Close $125.65 Range $111.25 - $147.63

Q1 2017

Shares 51,100 Value ($000) $2,619 Avg Close $46.22 Range $35.98 - $60.41

Q2 2016

Shares 18,673 Value ($000) $1,036 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 214,000 Value ($000) $13,433 Avg Close $66.49 Range $51.51 - $98.00

Q2 2015

Shares 102,399 Value ($000) $12,275 Avg Close $119.50 Range $98.63 - $140.00

Q1 2014

Shares 158,700 Value ($000) $10,655 Avg Close $77.42 Range $60.24 - $112.57

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2018	64,400	$5,636	$100.59	$86.95 - $124.22
Q2 2018	375,400	$36,973	$99.19	$87.35 - $118.71
Q1 2018	235,400	$28,036	$128.92	$108.13 - $153.99
Q4 2017	8,100	$1,029	$125.65	$111.25 - $147.63
Q1 2017	51,100	$2,619	$46.22	$35.98 - $60.41
Q2 2016	18,673	$1,036	$63.00	$49.96 - $75.08
Q1 2016	214,000	$13,433	$66.49	$51.51 - $98.00
Q2 2015	102,399	$12,275	$119.50	$98.63 - $140.00
Q1 2014	158,700	$10,655	$77.42	$60.24 - $112.57