ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

GREAT POINT PARTNERS LLC's Holding History (CIK: 0001281446)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018

Shares 40,197 Value ($000) $2,931 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 300,000 Value ($000) $26,256 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 260,100 Value ($000) $25,617 Avg Close $99.19 Range $87.35 - $118.71

Q2 2017

Shares 276,800 Value ($000) $22,078 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 11,517 Value ($000) $590 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 51,935 Value ($000) $1,944 Avg Close $41.87 Range $31.38 - $71.67

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2018	40,197	$2,931	$76.92	$60.27 - $90.00
Q3 2018	300,000	$26,256	$100.59	$86.95 - $124.22
Q2 2018	260,100	$25,617	$99.19	$87.35 - $118.71
Q2 2017	276,800	$22,078	$63.91	$46.90 - $86.92
Q1 2017	11,517	$590	$46.22	$35.98 - $60.41
Q4 2016	51,935	$1,944	$41.87	$31.38 - $71.67