ALUMIS INC

Ticker: ALMS CUSIP: 022307102 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 298,219 Value ($000) $2,911 Avg Close $6.98 Range $3.92 - $12.44

Q3 2025

Shares 86,084 Value ($000) $343 Avg Close $4.12 Range $2.92 - $5.13

Q1 2025

Shares 10,700 Value ($000) $66 Avg Close $5.82 Range $3.18 - $9.07

Q2 2024

Shares 19,000 Value ($000) $253 Avg Close $13.30 Range $12.02 - $13.53

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	298,219	$2,911	$6.98	$3.92 - $12.44
Q3 2025	86,084	$343	$4.12	$2.92 - $5.13
Q1 2025	10,700	$66	$5.82	$3.18 - $9.07
Q2 2024	19,000	$253	$13.30	$12.02 - $13.53