AMYLYX PHARMACEUTICALS INC

Ticker: AMLX CUSIP: 03237H101 Class: Common Stock

EVENTIDE ASSET MANAGEMENT, LLC's Holding History (CIK: 0001442891)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,513,148 Value ($000) $18,279 Avg Close $13.58 Range $11.69 - $16.96

Q3 2025

Shares 1,512,500 Value ($000) $20,555 Avg Close $9.41 Range $5.97 - $15.14

Q4 2023

Shares 1,116,837 Value ($000) $16,440 Avg Close $15.33 Range $11.82 - $18.88

Q3 2023

Shares 1,116,837 Value ($000) $20,449 Avg Close $21.15 Range $17.80 - $25.48

Q2 2023

Shares 1,116,837 Value ($000) $24,090 Avg Close $27.01 Range $20.79 - $31.77

Q1 2023

Shares 458,054 Value ($000) $13,439 Avg Close $34.74 Range $26.64 - $41.93

Q4 2022

Shares 250,000 Value ($000) $9,238 Avg Close $35.49 Range $28.13 - $39.77

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,513,148	$18,279	$13.58	$11.69 - $16.96
Q3 2025	1,512,500	$20,555	$9.41	$5.97 - $15.14
Q4 2023	1,116,837	$16,440	$15.33	$11.82 - $18.88
Q3 2023	1,116,837	$20,449	$21.15	$17.80 - $25.48
Q2 2023	1,116,837	$24,090	$27.01	$20.79 - $31.77
Q1 2023	458,054	$13,439	$34.74	$26.64 - $41.93
Q4 2022	250,000	$9,238	$35.49	$28.13 - $39.77