AMYLYX PHARMACEUTICALS INC

Ticker: AMLX CUSIP: 03237H101 Class: Common Stock

Sofinnova Investments, Inc.'s Holding History (CIK: 0001631134)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 527,099 Value ($000) $6,367 Avg Close $13.58 Range $11.69 - $16.96

Q2 2024

Shares 299,691 Value ($000) $569 Avg Close $1.94 Range $1.57 - $2.89

Q1 2024

Shares 306,729 Value ($000) $871 Avg Close $13.08 Range $2.67 - $19.95

Q2 2022

Shares 187,381 Value ($000) $3,609 Avg Close $11.87 Range $6.51 - $20.74

Q1 2022

Shares 100,000 Value ($000) $1,285 Avg Close $22.45 Range $10.49 - $33.41

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	527,099	$6,367	$13.58	$11.69 - $16.96
Q2 2024	299,691	$569	$1.94	$1.57 - $2.89
Q1 2024	306,729	$871	$13.08	$2.67 - $19.95
Q2 2022	187,381	$3,609	$11.87	$6.51 - $20.74
Q1 2022	100,000	$1,285	$22.45	$10.49 - $33.41