ANAPTYSBIO INC

Ticker: ANAB CUSIP: 032724106 Class: Common Stock

PFM Health Sciences, LP's Holding History (CIK: 0001442756)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018

Shares 605,345 Value ($000) $38,615 Avg Close $74.37 Range $54.26 - $100.97

Q3 2018

Shares 1,054,361 Value ($000) $105,194 Avg Close $82.97 Range $67.91 - $110.00

Q2 2018

Shares 138,338 Value ($000) $9,828 Avg Close $83.89 Range $66.39 - $108.57

Q1 2018

Shares 70,354 Value ($000) $7,322 Avg Close $112.70 Range $91.01 - $134.00

Q4 2017

Shares 425,896 Value ($000) $42,896 Avg Close $73.61 Range $34.56 - $102.63

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2018	605,345	$38,615	$74.37	$54.26 - $100.97
Q3 2018	1,054,361	$105,194	$82.97	$67.91 - $110.00
Q2 2018	138,338	$9,828	$83.89	$66.39 - $108.57
Q1 2018	70,354	$7,322	$112.70	$91.01 - $134.00
Q4 2017	425,896	$42,896	$73.61	$34.56 - $102.63