ANAVEX LIFE SCIENCES CORP

Ticker: AVXL CUSIP: 032797300 Class: Common Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 21,468 Value ($000) $76 Avg Close $6.13 Range $2.86 - $10.38

Q1 2019

Shares 18,597 Value ($000) $57 Avg Close $2.39 Range $1.48 - $4.00

Q2 2018

Shares 10,382 Value ($000) $27 Avg Close $2.79 Range $1.85 - $4.35

Q4 2017

Shares 10,478 Value ($000) $34 Avg Close $3.94 Range $3.01 - $5.15

Q3 2017

Shares 28,444 Value ($000) $118 Avg Close $4.44 Range $3.33 - $5.57

Q2 2017

Shares 13,549 Value ($000) $72 Avg Close $5.78 Range $5.10 - $6.49

Q1 2017

Shares 10,759 Value ($000) $62 Avg Close $5.16 Range $3.95 - $6.64

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	21,468	$76	$6.13	$2.86 - $10.38
Q1 2019	18,597	$57	$2.39	$1.48 - $4.00
Q2 2018	10,382	$27	$2.79	$1.85 - $4.35
Q4 2017	10,478	$34	$3.94	$3.01 - $5.15
Q3 2017	28,444	$118	$4.44	$3.33 - $5.57
Q2 2017	13,549	$72	$5.78	$5.10 - $6.49
Q1 2017	10,759	$62	$5.16	$3.95 - $6.64