ANIKA THERAPEUTICS INC

Ticker: ANIK CUSIP: 035255108 Class: COM

RENAISSANCE TECHNOLOGIES LLC's Holding History (CIK: 0001037389)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 515,717 Value ($000) $4,956 Avg Close $9.58 Range $8.67 - $10.75

Q3 2025

Shares 533,017 Value ($000) $5,010 Avg Close $9.55 Range $7.87 - $11.84

Q2 2025

Shares 527,217 Value ($000) $5,578 Avg Close $12.62 Range $10.47 - $15.45

Q1 2025

Shares 528,617 Value ($000) $7,945 Avg Close $16.64 Range $14.79 - $18.37

Q4 2024

Shares 528,517 Value ($000) $8,699 Avg Close $19.72 Range $15.83 - $25.65

Q3 2024

Shares 574,229 Value ($000) $14,183 Avg Close $25.93 Range $24.15 - $29.12

Q2 2024

Shares 598,229 Value ($000) $15,153 Avg Close $25.92 Range $23.92 - $28.67

Q1 2024

Shares 559,817 Value ($000) $14 Avg Close $24.20 Range $21.00 - $27.31

Q4 2023

Shares 564,329 Value ($000) $13 Avg Close $20.69 Range $17.88 - $24.25

Q3 2023

Shares 588,629 Value ($000) $11 Avg Close $20.74 Range $16.54 - $26.32

Q2 2023

Shares 633,229 Value ($000) $16 Avg Close $26.76 Range $24.49 - $29.26

Q1 2023

Shares 575,417 Value ($000) $17 Avg Close $29.76 Range $23.02 - $32.33

Q4 2022

Shares 595,529 Value ($000) $18 Avg Close $28.44 Range $23.19 - $32.51

Q3 2022

Shares 636,517 Value ($000) $15,149 Avg Close $23.01 Range $21.44 - $25.21

Q2 2022

Shares 705,817 Value ($000) $15,754 Avg Close $22.31 Range $19.95 - $25.67

Q1 2022

Shares 676,217 Value ($000) $16,980 Avg Close $30.49 Range $24.21 - $36.85

Q4 2021

Shares 683,417 Value ($000) $24,487 Avg Close $40.03 Range $35.65 - $45.81

Q3 2021

Shares 704,017 Value ($000) $29,963 Avg Close $41.19 Range $38.52 - $44.87

Q2 2021

Shares 718,717 Value ($000) $31,113 Avg Close $42.59 Range $38.88 - $48.37

Q1 2021

Shares 745,017 Value ($000) $30,389 Avg Close $37.93 Range $32.30 - $47.15

Q4 2020

Shares 809,117 Value ($000) $36,621 Avg Close $37.95 Range $32.04 - $47.48

Q3 2020

Shares 836,517 Value ($000) $29,604 Avg Close $36.12 Range $32.21 - $39.70

Q2 2020

Shares 834,917 Value ($000) $31,501 Avg Close $32.95 Range $27.38 - $38.17

Q1 2020

Shares 747,829 Value ($000) $21,620 Avg Close $40.45 Range $22.01 - $55.10

Q4 2019

Shares 585,129 Value ($000) $30,339 Avg Close $58.09 Range $51.37 - $75.72

Q3 2019

Shares 482,922 Value ($000) $26,508 Avg Close $51.34 Range $39.45 - $58.93

Q2 2019

Shares 444,222 Value ($000) $18,044 Avg Close $36.46 Range $29.98 - $41.88

Q1 2019

Shares 365,410 Value ($000) $11,050 Avg Close $34.25 Range $29.01 - $40.71

Q4 2018

Shares 263,133 Value ($000) $8,844 Avg Close $36.09 Range $29.58 - $43.45

Q3 2018

Shares 270,126 Value ($000) $11,394 Avg Close $39.51 Range $31.91 - $44.95

Q2 2018

Shares 317,500 Value ($000) $10,160 Avg Close $41.18 Range $28.54 - $49.75

Q1 2018

Shares 202,100 Value ($000) $10,048 Avg Close $56.50 Range $45.74 - $69.81

Q4 2017

Shares 109,700 Value ($000) $5,914 Avg Close $55.35 Range $51.10 - $60.29

Q3 2017

Shares 114,700 Value ($000) $6,653 Avg Close $52.27 Range $45.09 - $59.28

Q2 2017

Shares 144,900 Value ($000) $7,149 Avg Close $46.05 Range $42.51 - $49.99

Q1 2017

Shares 253,100 Value ($000) $10,995 Avg Close $47.74 Range $41.64 - $52.39

Q4 2016

Shares 166,800 Value ($000) $8,167 Avg Close $46.23 Range $41.38 - $50.19

Q3 2016

Shares 207,700 Value ($000) $9,938 Avg Close $49.40 Range $45.25 - $54.96

Q2 2016

Shares 271,100 Value ($000) $14,545 Avg Close $47.12 Range $42.36 - $53.68

Q1 2016

Shares 300,400 Value ($000) $13,434 Avg Close $40.56 Range $35.07 - $47.24

Q4 2015

Shares 113,000 Value ($000) $4,312 Avg Close $38.25 Range $30.94 - $43.82

Q3 2015

Shares 53,600 Value ($000) $1,706 Avg Close $34.87 Range $30.93 - $39.24

Q2 2015

Shares 117,200 Value ($000) $3,871 Avg Close $35.67 Range $31.36 - $41.30

Q1 2015

Shares 112,500 Value ($000) $4,632 Avg Close $40.43 Range $37.05 - $45.35

Q4 2014

Shares 212,800 Value ($000) $8,669 Avg Close $39.09 Range $34.16 - $43.24

Q3 2014

Shares 270,600 Value ($000) $9,920 Avg Close $43.21 Range $35.39 - $50.89

Q2 2014

Shares 367,400 Value ($000) $17,022 Avg Close $44.47 Range $35.62 - $51.40

Q1 2014

Shares 442,400 Value ($000) $18,183 Avg Close $37.17 Range $28.79 - $52.49

Q4 2013

Shares 396,800 Value ($000) $15,142 Avg Close $30.85 Range $23.26 - $38.68

Q3 2013

Shares 402,100 Value ($000) $9,606 Avg Close $22.45 Range $17.02 - $27.80

Q2 2013

Shares 370,703 Value ($000) $6,302 Avg Close $14.42 Range $12.26 - $18.07

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	515,717	$4,956	$9.58	$8.67 - $10.75
Q3 2025	533,017	$5,010	$9.55	$7.87 - $11.84
Q2 2025	527,217	$5,578	$12.62	$10.47 - $15.45
Q1 2025	528,617	$7,945	$16.64	$14.79 - $18.37
Q4 2024	528,517	$8,699	$19.72	$15.83 - $25.65
Q3 2024	574,229	$14,183	$25.93	$24.15 - $29.12
Q2 2024	598,229	$15,153	$25.92	$23.92 - $28.67
Q1 2024	559,817	$14	$24.20	$21.00 - $27.31
Q4 2023	564,329	$13	$20.69	$17.88 - $24.25
Q3 2023	588,629	$11	$20.74	$16.54 - $26.32
Q2 2023	633,229	$16	$26.76	$24.49 - $29.26
Q1 2023	575,417	$17	$29.76	$23.02 - $32.33
Q4 2022	595,529	$18	$28.44	$23.19 - $32.51
Q3 2022	636,517	$15,149	$23.01	$21.44 - $25.21
Q2 2022	705,817	$15,754	$22.31	$19.95 - $25.67
Q1 2022	676,217	$16,980	$30.49	$24.21 - $36.85
Q4 2021	683,417	$24,487	$40.03	$35.65 - $45.81
Q3 2021	704,017	$29,963	$41.19	$38.52 - $44.87
Q2 2021	718,717	$31,113	$42.59	$38.88 - $48.37
Q1 2021	745,017	$30,389	$37.93	$32.30 - $47.15
Q4 2020	809,117	$36,621	$37.95	$32.04 - $47.48
Q3 2020	836,517	$29,604	$36.12	$32.21 - $39.70
Q2 2020	834,917	$31,501	$32.95	$27.38 - $38.17
Q1 2020	747,829	$21,620	$40.45	$22.01 - $55.10
Q4 2019	585,129	$30,339	$58.09	$51.37 - $75.72
Q3 2019	482,922	$26,508	$51.34	$39.45 - $58.93
Q2 2019	444,222	$18,044	$36.46	$29.98 - $41.88
Q1 2019	365,410	$11,050	$34.25	$29.01 - $40.71
Q4 2018	263,133	$8,844	$36.09	$29.58 - $43.45
Q3 2018	270,126	$11,394	$39.51	$31.91 - $44.95
Q2 2018	317,500	$10,160	$41.18	$28.54 - $49.75
Q1 2018	202,100	$10,048	$56.50	$45.74 - $69.81
Q4 2017	109,700	$5,914	$55.35	$51.10 - $60.29
Q3 2017	114,700	$6,653	$52.27	$45.09 - $59.28
Q2 2017	144,900	$7,149	$46.05	$42.51 - $49.99
Q1 2017	253,100	$10,995	$47.74	$41.64 - $52.39
Q4 2016	166,800	$8,167	$46.23	$41.38 - $50.19
Q3 2016	207,700	$9,938	$49.40	$45.25 - $54.96
Q2 2016	271,100	$14,545	$47.12	$42.36 - $53.68
Q1 2016	300,400	$13,434	$40.56	$35.07 - $47.24
Q4 2015	113,000	$4,312	$38.25	$30.94 - $43.82
Q3 2015	53,600	$1,706	$34.87	$30.93 - $39.24
Q2 2015	117,200	$3,871	$35.67	$31.36 - $41.30
Q1 2015	112,500	$4,632	$40.43	$37.05 - $45.35
Q4 2014	212,800	$8,669	$39.09	$34.16 - $43.24
Q3 2014	270,600	$9,920	$43.21	$35.39 - $50.89
Q2 2014	367,400	$17,022	$44.47	$35.62 - $51.40
Q1 2014	442,400	$18,183	$37.17	$28.79 - $52.49
Q4 2013	396,800	$15,142	$30.85	$23.26 - $38.68
Q3 2013	402,100	$9,606	$22.45	$17.02 - $27.80
Q2 2013	370,703	$6,302	$14.42	$12.26 - $18.07