ANNEXON INC

Ticker: ANNX CUSIP: 03589W102 Class: COM

Brevan Howard Capital Management LP's Holding History (CIK: 0001512857)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 123,753 Value ($000) $621 Avg Close $3.82 Range $2.54 - $5.48

Q3 2025

Shares 94,554 Value ($000) $288 Avg Close $2.48 Range $1.85 - $3.42

Q2 2025

Shares 53,283 Value ($000) $128 Avg Close $2.00 Range $1.28 - $2.82

Q1 2025

Shares 62,074 Value ($000) $120 Avg Close $3.33 Range $1.93 - $5.66

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	123,753	$621	$3.82	$2.54 - $5.48
Q3 2025	94,554	$288	$2.48	$1.85 - $3.42
Q2 2025	53,283	$128	$2.00	$1.28 - $2.82
Q1 2025	62,074	$120	$3.33	$1.93 - $5.66