APELLIS PHARMACEUTICALS INC

Ticker: APLS CUSIP: 03753U106 Class: Common Stock

STATE OF WISCONSIN INVESTMENT BOARD's Holding History (CIK: 0000854157)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 66,916 Value ($000) $1,681 Avg Close $23.46 Range $18.75 - $30.48

Q3 2025

Shares 85,761 Value ($000) $1,941 Avg Close $23.32 Range $17.35 - $28.97

Q2 2025

Shares 94,404 Value ($000) $1,634 Avg Close $18.51 Range $16.10 - $23.77

Q1 2025

Shares 84,615 Value ($000) $1,851 Avg Close $27.62 Range $21.70 - $35.57

Q4 2024

Shares 80,382 Value ($000) $2,565 Avg Close $30.07 Range $24.34 - $35.72

Q3 2024

Shares 81,039 Value ($000) $2,337 Avg Close $37.03 Range $28.32 - $42.47

Q2 2024

Shares 77,349 Value ($000) $2,967 Avg Close $45.29 Range $37.00 - $59.91

Q1 2024

Shares 51,675 Value ($000) $3,037 Avg Close $63.75 Range $53.19 - $73.80

Q4 2023

Shares 67,805 Value ($000) $4,059 Avg Close $50.73 Range $36.31 - $66.30

Q3 2023

Shares 82,772 Value ($000) $3,149 Avg Close $43.93 Range $19.83 - $91.35

Q2 2023

Shares 76,820 Value ($000) $6,998 Avg Close $86.28 Range $73.80 - $94.75

Q1 2023

Shares 81,584 Value ($000) $5,381 Avg Close $57.70 Range $44.92 - $70.75

Q4 2022

Shares 88,158 Value ($000) $4,559 Avg Close $53.04 Range $42.15 - $66.80

Q3 2022

Shares 81,190 Value ($000) $5,545 Avg Close $59.17 Range $44.07 - $70.00

Q2 2022

Shares 83,116 Value ($000) $3,759 Avg Close $45.59 Range $33.32 - $60.20

Q1 2022

Shares 95,700 Value ($000) $4,863 Avg Close $44.15 Range $33.50 - $54.51

Q4 2021

Shares 95,700 Value ($000) $4,525 Avg Close $39.37 Range $30.17 - $50.31

Q3 2021

Shares 90,000 Value ($000) $2,966 Avg Close $56.19 Range $27.50 - $73.00

Q2 2021

Shares 80,900 Value ($000) $5,113 Avg Close $51.60 Range $40.53 - $66.07

Q1 2021

Shares 80,900 Value ($000) $3,471 Avg Close $47.32 Range $39.95 - $58.47

Q4 2020

Shares 85,600 Value ($000) $4,896 Avg Close $42.30 Range $29.80 - $58.03

Q3 2020

Shares 96,300 Value ($000) $2,905 Avg Close $29.88 Range $25.49 - $34.08

Q2 2020

Shares 96,300 Value ($000) $3,145 Avg Close $32.11 Range $24.34 - $39.98

Q1 2020

Shares 194,305 Value ($000) $5,205 Avg Close $35.50 Range $16.85 - $45.04

Q4 2019

Shares 72,200 Value ($000) $2,211 Avg Close $27.68 Range $21.79 - $31.47

Q3 2019

Shares 72,200 Value ($000) $1,739 Avg Close $27.52 Range $23.83 - $33.18

Q2 2019

Shares 52,000 Value ($000) $1,318 Avg Close $20.35 Range $17.36 - $25.41

Q1 2019

Shares 50,900 Value ($000) $993 Avg Close $15.73 Range $12.50 - $20.03

Q4 2018

Shares 37,100 Value ($000) $489 Avg Close $15.34 Range $11.45 - $20.54

Q3 2018

Shares 36,800 Value ($000) $654 Avg Close $18.48 Range $16.25 - $21.93

Q2 2018

Shares 36,800 Value ($000) $810 Avg Close $22.98 Range $18.89 - $32.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	66,916	$1,681	$23.46	$18.75 - $30.48
Q3 2025	85,761	$1,941	$23.32	$17.35 - $28.97
Q2 2025	94,404	$1,634	$18.51	$16.10 - $23.77
Q1 2025	84,615	$1,851	$27.62	$21.70 - $35.57
Q4 2024	80,382	$2,565	$30.07	$24.34 - $35.72
Q3 2024	81,039	$2,337	$37.03	$28.32 - $42.47
Q2 2024	77,349	$2,967	$45.29	$37.00 - $59.91
Q1 2024	51,675	$3,037	$63.75	$53.19 - $73.80
Q4 2023	67,805	$4,059	$50.73	$36.31 - $66.30
Q3 2023	82,772	$3,149	$43.93	$19.83 - $91.35
Q2 2023	76,820	$6,998	$86.28	$73.80 - $94.75
Q1 2023	81,584	$5,381	$57.70	$44.92 - $70.75
Q4 2022	88,158	$4,559	$53.04	$42.15 - $66.80
Q3 2022	81,190	$5,545	$59.17	$44.07 - $70.00
Q2 2022	83,116	$3,759	$45.59	$33.32 - $60.20
Q1 2022	95,700	$4,863	$44.15	$33.50 - $54.51
Q4 2021	95,700	$4,525	$39.37	$30.17 - $50.31
Q3 2021	90,000	$2,966	$56.19	$27.50 - $73.00
Q2 2021	80,900	$5,113	$51.60	$40.53 - $66.07
Q1 2021	80,900	$3,471	$47.32	$39.95 - $58.47
Q4 2020	85,600	$4,896	$42.30	$29.80 - $58.03
Q3 2020	96,300	$2,905	$29.88	$25.49 - $34.08
Q2 2020	96,300	$3,145	$32.11	$24.34 - $39.98
Q1 2020	194,305	$5,205	$35.50	$16.85 - $45.04
Q4 2019	72,200	$2,211	$27.68	$21.79 - $31.47
Q3 2019	72,200	$1,739	$27.52	$23.83 - $33.18
Q2 2019	52,000	$1,318	$20.35	$17.36 - $25.41
Q1 2019	50,900	$993	$15.73	$12.50 - $20.03
Q4 2018	37,100	$489	$15.34	$11.45 - $20.54
Q3 2018	36,800	$654	$18.48	$16.25 - $21.93
Q2 2018	36,800	$810	$22.98	$18.89 - $32.00