APELLIS PHARMACEUTICALS INC

Ticker: APLS CUSIP: 03753U106 Class: Common Stock

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM's Holding History (CIK: 0001081019)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 73,203 Value ($000) $1,839 Avg Close $23.46 Range $18.75 - $30.48

Q3 2025

Shares 73,298 Value ($000) $1,659 Avg Close $23.32 Range $17.35 - $28.97

Q2 2025

Shares 87,929 Value ($000) $1,522 Avg Close $18.51 Range $16.10 - $23.77

Q1 2025

Shares 59,778 Value ($000) $1,307 Avg Close $27.62 Range $21.70 - $35.57

Q4 2024

Shares 70,688 Value ($000) $2,256 Avg Close $30.07 Range $24.34 - $35.72

Q3 2024

Shares 76,540 Value ($000) $2,207 Avg Close $37.03 Range $28.32 - $42.47

Q2 2024

Shares 78,702 Value ($000) $3,019 Avg Close $45.29 Range $37.00 - $59.91

Q1 2024

Shares 74,370 Value ($000) $4,371 Avg Close $63.75 Range $53.19 - $73.80

Q4 2023

Shares 90,191 Value ($000) $5,399 Avg Close $50.73 Range $36.31 - $66.30

Q3 2023

Shares 94,269 Value ($000) $3,586 Avg Close $43.93 Range $19.83 - $91.35

Q2 2023

Shares 104,487 Value ($000) $9,519 Avg Close $86.28 Range $73.80 - $94.75

Q1 2023

Shares 112,603 Value ($000) $7,427 Avg Close $57.70 Range $44.92 - $70.75

Q4 2022

Shares 113,909 Value ($000) $5,890 Avg Close $53.04 Range $42.15 - $66.80

Q3 2022

Shares 110,360 Value ($000) $7,538 Avg Close $59.17 Range $44.07 - $70.00

Q2 2022

Shares 105,614 Value ($000) $4,776 Avg Close $45.59 Range $33.32 - $60.20

Q1 2022

Shares 98,930 Value ($000) $5,027 Avg Close $44.15 Range $33.50 - $54.51

Q4 2021

Shares 103,701 Value ($000) $4,903 Avg Close $39.37 Range $30.17 - $50.31

Q3 2021

Shares 84,617 Value ($000) $2,789 Avg Close $56.19 Range $27.50 - $73.00

Q2 2021

Shares 89,522 Value ($000) $5,658 Avg Close $51.60 Range $40.53 - $66.07

Q1 2021

Shares 90,557 Value ($000) $3,886 Avg Close $47.32 Range $39.95 - $58.47

Q4 2020

Shares 90,830 Value ($000) $5,195 Avg Close $42.30 Range $29.80 - $58.03

Q3 2020

Shares 90,923 Value ($000) $2,743 Avg Close $29.88 Range $25.49 - $34.08

Q2 2020

Shares 90,546 Value ($000) $2,957 Avg Close $32.11 Range $24.34 - $39.98

Q1 2020

Shares 86,974 Value ($000) $2,330 Avg Close $35.50 Range $16.85 - $45.04

Q4 2019

Shares 74,591 Value ($000) $2,284 Avg Close $27.68 Range $21.79 - $31.47

Q3 2019

Shares 75,326 Value ($000) $1,815 Avg Close $27.52 Range $23.83 - $33.18

Q2 2019

Shares 74,417 Value ($000) $1,886 Avg Close $20.35 Range $17.36 - $25.41

Q1 2019

Shares 55,297 Value ($000) $1,078 Avg Close $15.73 Range $12.50 - $20.03

Q4 2018

Shares 56,645 Value ($000) $747 Avg Close $15.34 Range $11.45 - $20.54

Q3 2018

Shares 55,268 Value ($000) $983 Avg Close $18.48 Range $16.25 - $21.93

Q2 2018

Shares 55,271 Value ($000) $1,216 Avg Close $22.98 Range $18.89 - $32.00

Q1 2018

Shares 16,727 Value ($000) $370 Avg Close $19.65 Range $13.54 - $27.53

Q4 2017

Shares 17,066 Value ($000) $370 Avg Close $14.72 Range $12.45 - $24.17

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	73,203	$1,839	$23.46	$18.75 - $30.48
Q3 2025	73,298	$1,659	$23.32	$17.35 - $28.97
Q2 2025	87,929	$1,522	$18.51	$16.10 - $23.77
Q1 2025	59,778	$1,307	$27.62	$21.70 - $35.57
Q4 2024	70,688	$2,256	$30.07	$24.34 - $35.72
Q3 2024	76,540	$2,207	$37.03	$28.32 - $42.47
Q2 2024	78,702	$3,019	$45.29	$37.00 - $59.91
Q1 2024	74,370	$4,371	$63.75	$53.19 - $73.80
Q4 2023	90,191	$5,399	$50.73	$36.31 - $66.30
Q3 2023	94,269	$3,586	$43.93	$19.83 - $91.35
Q2 2023	104,487	$9,519	$86.28	$73.80 - $94.75
Q1 2023	112,603	$7,427	$57.70	$44.92 - $70.75
Q4 2022	113,909	$5,890	$53.04	$42.15 - $66.80
Q3 2022	110,360	$7,538	$59.17	$44.07 - $70.00
Q2 2022	105,614	$4,776	$45.59	$33.32 - $60.20
Q1 2022	98,930	$5,027	$44.15	$33.50 - $54.51
Q4 2021	103,701	$4,903	$39.37	$30.17 - $50.31
Q3 2021	84,617	$2,789	$56.19	$27.50 - $73.00
Q2 2021	89,522	$5,658	$51.60	$40.53 - $66.07
Q1 2021	90,557	$3,886	$47.32	$39.95 - $58.47
Q4 2020	90,830	$5,195	$42.30	$29.80 - $58.03
Q3 2020	90,923	$2,743	$29.88	$25.49 - $34.08
Q2 2020	90,546	$2,957	$32.11	$24.34 - $39.98
Q1 2020	86,974	$2,330	$35.50	$16.85 - $45.04
Q4 2019	74,591	$2,284	$27.68	$21.79 - $31.47
Q3 2019	75,326	$1,815	$27.52	$23.83 - $33.18
Q2 2019	74,417	$1,886	$20.35	$17.36 - $25.41
Q1 2019	55,297	$1,078	$15.73	$12.50 - $20.03
Q4 2018	56,645	$747	$15.34	$11.45 - $20.54
Q3 2018	55,268	$983	$18.48	$16.25 - $21.93
Q2 2018	55,271	$1,216	$22.98	$18.89 - $32.00
Q1 2018	16,727	$370	$19.65	$13.54 - $27.53
Q4 2017	17,066	$370	$14.72	$12.45 - $24.17