APELLIS PHARMACEUTICALS INC

Ticker: APLS CUSIP: 03753U106 Class: Common Stock

MILLENNIUM MANAGEMENT LLC's Holding History (CIK: 0001273087)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 946,459 Value ($000) $23,775 Avg Close $23.46 Range $18.75 - $30.48

Q3 2025

Shares 1,343,726 Value ($000) $30,409 Avg Close $23.32 Range $17.35 - $28.97

Q2 2025

Shares 202,452 Value ($000) $3,504 Avg Close $18.51 Range $16.10 - $23.77

Q1 2025

Shares 451,973 Value ($000) $9,885 Avg Close $27.62 Range $21.70 - $35.57

Q4 2024

Shares 575,490 Value ($000) $18,364 Avg Close $30.07 Range $24.34 - $35.72

Q3 2024

Shares 77,386 Value ($000) $2,232 Avg Close $37.03 Range $28.32 - $42.47

Q2 2024

Shares 205,911 Value ($000) $7,899 Avg Close $45.29 Range $37.00 - $59.91

Q1 2024

Shares 785,396 Value ($000) $46,166 Avg Close $63.75 Range $53.19 - $73.80

Q4 2023

Shares 12,527 Value ($000) $750 Avg Close $50.73 Range $36.31 - $66.30

Q3 2023

Shares 45,129 Value ($000) $1,717 Avg Close $43.93 Range $19.83 - $91.35

Q2 2023

Shares 918,811 Value ($000) $83,704 Avg Close $86.28 Range $73.80 - $94.75

Q1 2023

Shares 548,201 Value ($000) $36 Avg Close $57.70 Range $44.92 - $70.75

Q4 2022

Shares 19,636 Value ($000) $1 Avg Close $53.04 Range $42.15 - $66.80

Q3 2022

Shares 257,869 Value ($000) $17,612 Avg Close $59.17 Range $44.07 - $70.00

Q1 2022

Shares 60,505 Value ($000) $3,074 Avg Close $44.15 Range $33.50 - $54.51

Q4 2021

Shares 312,002 Value ($000) $14,751 Avg Close $39.37 Range $30.17 - $50.31

Q3 2021

Shares 405,382 Value ($000) $13,361 Avg Close $56.19 Range $27.50 - $73.00

Q1 2021

Shares 158,571 Value ($000) $6,804 Avg Close $47.32 Range $39.95 - $58.47

Q4 2020

Shares 241,714 Value ($000) $13,826 Avg Close $42.30 Range $29.80 - $58.03

Q3 2020

Shares 916,703 Value ($000) $27,657 Avg Close $29.88 Range $25.49 - $34.08

Q2 2020

Shares 1,075,250 Value ($000) $35,118 Avg Close $32.11 Range $24.34 - $39.98

Q1 2020

Shares 1,357,586 Value ($000) $36,370 Avg Close $35.50 Range $16.85 - $45.04

Q4 2019

Shares 582,606 Value ($000) $17,839 Avg Close $27.68 Range $21.79 - $31.47

Q3 2019

Shares 2,711,261 Value ($000) $65,314 Avg Close $27.52 Range $23.83 - $33.18

Q2 2019

Shares 2,043,924 Value ($000) $51,793 Avg Close $20.35 Range $17.36 - $25.41

Q1 2019

Shares 1,926,566 Value ($000) $37,568 Avg Close $15.73 Range $12.50 - $20.03

Q4 2018

Shares 1,182,385 Value ($000) $15,596 Avg Close $15.34 Range $11.45 - $20.54

Q3 2018

Shares 1,107,109 Value ($000) $19,684 Avg Close $18.48 Range $16.25 - $21.93

Q2 2018

Shares 893,460 Value ($000) $19,656 Avg Close $22.98 Range $18.89 - $32.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	946,459	$23,775	$23.46	$18.75 - $30.48
Q3 2025	1,343,726	$30,409	$23.32	$17.35 - $28.97
Q2 2025	202,452	$3,504	$18.51	$16.10 - $23.77
Q1 2025	451,973	$9,885	$27.62	$21.70 - $35.57
Q4 2024	575,490	$18,364	$30.07	$24.34 - $35.72
Q3 2024	77,386	$2,232	$37.03	$28.32 - $42.47
Q2 2024	205,911	$7,899	$45.29	$37.00 - $59.91
Q1 2024	785,396	$46,166	$63.75	$53.19 - $73.80
Q4 2023	12,527	$750	$50.73	$36.31 - $66.30
Q3 2023	45,129	$1,717	$43.93	$19.83 - $91.35
Q2 2023	918,811	$83,704	$86.28	$73.80 - $94.75
Q1 2023	548,201	$36	$57.70	$44.92 - $70.75
Q4 2022	19,636	$1	$53.04	$42.15 - $66.80
Q3 2022	257,869	$17,612	$59.17	$44.07 - $70.00
Q1 2022	60,505	$3,074	$44.15	$33.50 - $54.51
Q4 2021	312,002	$14,751	$39.37	$30.17 - $50.31
Q3 2021	405,382	$13,361	$56.19	$27.50 - $73.00
Q1 2021	158,571	$6,804	$47.32	$39.95 - $58.47
Q4 2020	241,714	$13,826	$42.30	$29.80 - $58.03
Q3 2020	916,703	$27,657	$29.88	$25.49 - $34.08
Q2 2020	1,075,250	$35,118	$32.11	$24.34 - $39.98
Q1 2020	1,357,586	$36,370	$35.50	$16.85 - $45.04
Q4 2019	582,606	$17,839	$27.68	$21.79 - $31.47
Q3 2019	2,711,261	$65,314	$27.52	$23.83 - $33.18
Q2 2019	2,043,924	$51,793	$20.35	$17.36 - $25.41
Q1 2019	1,926,566	$37,568	$15.73	$12.50 - $20.03
Q4 2018	1,182,385	$15,596	$15.34	$11.45 - $20.54
Q3 2018	1,107,109	$19,684	$18.48	$16.25 - $21.93
Q2 2018	893,460	$19,656	$22.98	$18.89 - $32.00