APELLIS PHARMACEUTICALS INC

Ticker: APLS CUSIP: 03753U106 Class: Common Stock

DAFNA Capital Management LLC's Holding History (CIK: 0001389933)

Note: Option positions (PUT/CALL) are excluded.

Q1 2023

Shares 57,746 Value ($000) $3,809 Avg Close $57.70 Range $44.92 - $70.75

Q4 2022

Shares 83,446 Value ($000) $4,315 Avg Close $53.04 Range $42.15 - $66.80

Q3 2022

Shares 65,946 Value ($000) $4,504 Avg Close $59.17 Range $44.07 - $70.00

Q2 2022

Shares 96,935 Value ($000) $4,383 Avg Close $45.59 Range $33.32 - $60.20

Q1 2022

Shares 93,935 Value ($000) $4,773 Avg Close $44.15 Range $33.50 - $54.51

Q2 2021

Shares 12,703 Value ($000) $803 Avg Close $51.60 Range $40.53 - $66.07

Q1 2021

Shares 44,926 Value ($000) $1,928 Avg Close $47.32 Range $39.95 - $58.47

Q4 2020

Shares 43,916 Value ($000) $2,512 Avg Close $42.30 Range $29.80 - $58.03

Q3 2020

Shares 30,054 Value ($000) $907 Avg Close $29.88 Range $25.49 - $34.08

Q2 2020

Shares 33,554 Value ($000) $1,096 Avg Close $32.11 Range $24.34 - $39.98

Q1 2020

Shares 54,054 Value ($000) $1,448 Avg Close $35.50 Range $16.85 - $45.04

Q4 2019

Shares 40,657 Value ($000) $1,245 Avg Close $27.68 Range $21.79 - $31.47

Q3 2019

Shares 169,800 Value ($000) $4,090 Avg Close $27.52 Range $23.83 - $33.18

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2023	57,746	$3,809	$57.70	$44.92 - $70.75
Q4 2022	83,446	$4,315	$53.04	$42.15 - $66.80
Q3 2022	65,946	$4,504	$59.17	$44.07 - $70.00
Q2 2022	96,935	$4,383	$45.59	$33.32 - $60.20
Q1 2022	93,935	$4,773	$44.15	$33.50 - $54.51
Q2 2021	12,703	$803	$51.60	$40.53 - $66.07
Q1 2021	44,926	$1,928	$47.32	$39.95 - $58.47
Q4 2020	43,916	$2,512	$42.30	$29.80 - $58.03
Q3 2020	30,054	$907	$29.88	$25.49 - $34.08
Q2 2020	33,554	$1,096	$32.11	$24.34 - $39.98
Q1 2020	54,054	$1,448	$35.50	$16.85 - $45.04
Q4 2019	40,657	$1,245	$27.68	$21.79 - $31.47
Q3 2019	169,800	$4,090	$27.52	$23.83 - $33.18